Organometallic Compounds
Chem-Impex International, Inc. 1-(Trimethylsilyl)imidazole | MFCD00005280 | 250G
1-(Trimethylsilyl)imidazole, MFCD00005280, 250G
Medchemexpress LLC PS-1145 | 431898-65-6 | 99.7% | 322.75 | 50 MG
PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM. It blocks TNFα-induced NF-κB activation in MM cells by inhibiting IκBα phosphorylation. Dexamethasone enhances the blockade of NF-κB activation by PS-1145.
- Blocks TNFα-induced NF-κB activation.
- Inhibits IκBα phosphorylation.
- Enhances blockade of NF-κB activation by Dexamethasone.
- Blocks protective effect of IL-6 against Dex-induced apoptosis.
- Inhibits TNFα-induced intracellular adhesion molecule (ICAM)-1 expression.
- Inhibits IL-6 secretion from bone marrow stromal cells.
- Inhibits proliferation of MM cells adherent to bone marrow stromal cells.
Medchemexpress LLC 4-fluoro-3-(4-hydroxypiperidin-1-yl)sulfonyl-N-(3,4,5-trifluorophenyl)benzamide | 1445790-55-5 | 99.9% | 432.39 g/mol | C18H16F4N2O4S | 10MM 1ML
NVR 3-778 is a small-molecule hepatitis B virus (HBV) capsid assembly modulator (CAM) of the sulfamoylbenzamide class with reported oral bioavailability and anti-HBV activity. It is supplied for research use as a high-purity solid and is commonly provided as 10 mM stock solutions in DMSO for in vitro assays.
- First-in-class capsid assembly modulator for HBV research.
- Orally bioavailable compound with reported antiviral activity.
- High purity (≈99.9%) suitable for analytical and biological studies.
- Molecular weight 432.39 g/mol; formula C18H16F4N2O4S.
- Available as solid and as 10 mM DMSO solution for convenience in assays.
Medchemexpress LLC AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 100 MG
AK-778-XXMU | 1227045-76-2 | 99.9% | C22H17ClN2O3 | 100 MG
Apexbio Technology LLC NVR 3-778 1445790-55-5 10mg
NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | MFCD16882561; MFCD08272115 | 100.0% | 392.83 g/mol | C22H17ClN2O3 | 5 MG
A potent small-molecule research reagent that antagonizes DNA binding protein 2 (ID2), with demonstrated binding (KD ≈129 nM) and cellular activity inhibiting glioma cell migration and inducing apoptosis.
- Small-molecule antagonist of DNA binding protein 2 (ID2) with KD ≈129 nM.
- Inhibits glioma cell migration and invasion, and induces apoptosis in cell models.
- High purity (99.96%) and off-white to light yellow solid appearance.
- Molecular formula C22H17ClN2O3; molecular weight 392.83 g/mol.
- Recommended solvent: DMSO, 100 mg/mL (use ultrasonic and freshly opened DMSO).
- Storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solution store at -80°C.
Matrix Scientific 1-(TRIMETHYLSILYL)IMIDAZOL-25G
1-(Trimethylsilyl)imidazole, 97%; 25g,C6H12N2Si, MFCD00005280, mw 140.26, [18156-74-6]
TARGETMOL CHEMICALS INC PLATYCODIN D 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Platycodin D may stimulate TNF-(alpha) synthesis or inhibit degradation of TNF-(alpha) mRNA. Platycodin D (10/30 uM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA). Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization. purity: 99%
eMolecules Combi-Blocks Inc Bromodifluoromethyl diethylphosphonate 1kg 873647984 QA-4958 95 000 65094-22-6 MFCD00069118 267 007 C5H10BrF2O3P
Combi-Blocks Inc Bromodifluoromethyl diethylphosphonate 1kg 873647984 QA-4958 95 000 65094-22-6 MFCD00069118 267 007 C5H10BrF2O3P
Aobchem Benzylboronic acid pinacol ester, AOBCHEM USA 10364-5G. 87100-28-5. MFCD05663841
Benzylboronic acid pinacol ester, AOBCHEM USA 10364-5G. 87100-28-5. MFCD05663841